Audit Dosimetri pada Teknik IMRT/VMAT Terapi Radiasi pada Linear Accelarator (LINAC)
Abstract
Dosimetric audit is crucial in ensuring and improving the quality of radiation therapy, particularly in the field of radiotherapy using techniques such as Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT). This study employs a literature review methodology, analyzing and comparing 15 articles based on dosimeters and modalities. The results indicate that various dosimetric audit methods, including the use of glass dosimeters, Gafchromic films, ion chambers, and EPID, provide accurate results in measuring doses for IMRT and VMAT techniques using LINAC. Most studies show good success rates, with dose differences between the dosimeter and the planned dose within the tolerance limits of ±5%. However, some studies also report significant dose variations, especially in organs at risk (OAR) and areas with steep dose gradients. This study highlights that routine dosimetric audits and the use of appropriate detection technologies are essential to improving the precision and safety of radiation therapy for patients.
Downloads
Download data is not yet available.
References
[1] P. Kazantsev at al., ”IAEA methodology for on-site end-to-end IMRT/ VMAT audits: an international pilot study,” Acta Oncologica, vol. 59, no. 2, pp. 141-148, 2020, doi:10.1080/0284186X.2019.1685128.
[2] P. B. Greer et al., ” Experience with remote electronic portal imaging device-based dosimetric auditing for static and rotational intensity modulated radiotherapy;” J. Pre-Proof, Nov, 2024, doi: 10.1016/j.phro.2024.100674.
[3] I. Wulandari et al., ”Penatalaksanaan Radioterapi Kanker Payudara Teknik IMRT,” J. Radiografer Indonesia.
[4] D. M. Ghemis et al., ”Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam matched linacs: a three-institutional study,” Radiation Oncology, vol. 18, no. 126, 2023, doi:10.1186/s13014-023-02313-5.
[5] A. H. Waheeb et al., ” Comparison between different Dosimetric Tools based on Intensity-modulated Radiotherapy (IMRT): A Phantom Study,” NeuroQuantology, vol. 19, no. 11, pp. 141-150, Nov, 2021, doi:10.14704/nq.2021.19.11.NQ21184.
[6] M. Nakamura et al., ”A virtual audit system for intensity-modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study,” J Appl Clin Med Phys, vol. 24, no. 1-9, April, 2023, doi:10.1002/acm2.14040.
[7] S. Roy et al., ”Application of a Comprehensive Treatment Planning Test for Credentialing Intensity Modulated Radiotherapy and RapidArc in a TrueBeam Linear Accelerator Setup,” J. Medical Physics, vol. 48, Juny, 2023, doi: 10.4103/jmp.jmp_56_22.
[8] P. Kumar at al., ” Multi institutional dose audit in radiotherapy facilities using in house developed optically stimulated luminescence disc dosimeters,” J. Cancer Research and Therapeutics, vol. 19, no. 1, Feb. 2022.
[9] M. Ghazal et al., ’’ Dosimetric and mechanical equivalency of Varian TrueBeam linear accelerators,’’ J. Appl Clin Med Phys, vol. 22, no. 12, pp. 43-53, September, 2020, doi: 10.1002/acm2.13058.
[10] Kh. Masood et al., ” Comparison of level-I, -II and -III dosimetry quality audits for MV-photon beams emitted from medical linear accelerators,” International Journal of Radiation Research, vol. 18, no. 3, pp. 505-510, july, 2020, doi: 10.18869/acadpub.ijrr.18.3.505.
[11] C. F. Yeap et al., ”Development of a Fluence Generating Programme for Patient Specific Quality Assurance and Calibration of an Amorphous Silicon EPID,” Journal of Physics, 2020, doi:10.1088/1742-6596/1505/1/012004.
[12] G. Razinskas et al., ” Sensitivity and Specificity of Varian Halycon’s Portal Dosimetry for Plan-Specific Pre-Treatment QA,” Journal of Applied Clinical Medical Physics , April, 2023, doi: 10.1002/acm2.14001.
[13] I. Mrcela et al., ”Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients,” Acta Clin Croat, vol. 61, 2022, doi: 10.20471/acc.2022.61.s3.3.
[14] K. B. Kim, S. H. Choi., ’’ Postal Dosimetry Audits for the Domestic Medical Linear Accelerator,’’ Progress in Medical Physics. Vol. 31, no 2, June, 2020.
[15] K. M. Sergieva, ”Dosimetry Audit in Modern Radiotherapy,” Queen Giovanna University Hospital, Sofia Medical University, Sofia, Bulgaria.
[16] L. Duan et al., ” Evaluation of Complexity and Deliverability of IMRT Treatment Plans for Breast Cancer,” Department of Radiation Oncology, 2023, doi: 10.1038/s41598-023-48331-x.
[17] M. C. Glenn et al., ”Photon beam modeling variations predict errors in IMRT dosimetry audits,” J. Radiotherapy and Oncology, vol. 8, no. 14, 2022, doi:10.1016/j.radonc.2021.10.021.
[18] M. E. Kafhali et al., ” Clinical Experiment on Quality Control Comparison of Complex Treatment Plans of the VMAT Technique Using a Diode-Based Cylindrical Phantom (ArcCHECK) and an Amorphous Silicon-Based Planar Detctor (A-Si1000).” Elsevier B.V, vol. 12, November, 2021, doi: 10.1016/j.phmed.2021.100044.
[19] N. Dogan et al., ” Use of Electronic Portal Imaging Devices for Pre-Treatment andin vivo Dosimetry Patient-Specific IMRT and VMAT QA: Report of AAPM Task Group 307,” Med Phys, vol. 50, July, 2023, doi:10.1002/mp.16536.
[20] N. R. Kakade et al., ”Dosimetry audit in advanced radiotherapy using in-house developed anthropomorphic head & neck phantom,” Biomed. Phys. Eng. Express, vol. 10, Feb, 2024, doi:10.1088/2057-1976/ad222a.
[21] P. N. Mobit et al., ”End-to-End Test for a Radiotherapy Program Based on the Medical Linear Accelerator Installed in a Resource-Limited Oncology Centre in Sub-Saharan Africa,” Radiation Science and Technology, vol. 8, no. 2, pp. 22-29, doi: 10.11648/j.rst.20220802.1.
[22] F. C. D Zamo et al., ” Patient specific quality assurance of volumetric modulated arc therapy of synchronous bilateral breast cancer,” American Association of Medical Dosimetrists, vol. 49, November, 2023, doi: 10.1016/j.meddos.2023.11.003.
[2] P. B. Greer et al., ” Experience with remote electronic portal imaging device-based dosimetric auditing for static and rotational intensity modulated radiotherapy;” J. Pre-Proof, Nov, 2024, doi: 10.1016/j.phro.2024.100674.
[3] I. Wulandari et al., ”Penatalaksanaan Radioterapi Kanker Payudara Teknik IMRT,” J. Radiografer Indonesia.
[4] D. M. Ghemis et al., ”Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam matched linacs: a three-institutional study,” Radiation Oncology, vol. 18, no. 126, 2023, doi:10.1186/s13014-023-02313-5.
[5] A. H. Waheeb et al., ” Comparison between different Dosimetric Tools based on Intensity-modulated Radiotherapy (IMRT): A Phantom Study,” NeuroQuantology, vol. 19, no. 11, pp. 141-150, Nov, 2021, doi:10.14704/nq.2021.19.11.NQ21184.
[6] M. Nakamura et al., ”A virtual audit system for intensity-modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study,” J Appl Clin Med Phys, vol. 24, no. 1-9, April, 2023, doi:10.1002/acm2.14040.
[7] S. Roy et al., ”Application of a Comprehensive Treatment Planning Test for Credentialing Intensity Modulated Radiotherapy and RapidArc in a TrueBeam Linear Accelerator Setup,” J. Medical Physics, vol. 48, Juny, 2023, doi: 10.4103/jmp.jmp_56_22.
[8] P. Kumar at al., ” Multi institutional dose audit in radiotherapy facilities using in house developed optically stimulated luminescence disc dosimeters,” J. Cancer Research and Therapeutics, vol. 19, no. 1, Feb. 2022.
[9] M. Ghazal et al., ’’ Dosimetric and mechanical equivalency of Varian TrueBeam linear accelerators,’’ J. Appl Clin Med Phys, vol. 22, no. 12, pp. 43-53, September, 2020, doi: 10.1002/acm2.13058.
[10] Kh. Masood et al., ” Comparison of level-I, -II and -III dosimetry quality audits for MV-photon beams emitted from medical linear accelerators,” International Journal of Radiation Research, vol. 18, no. 3, pp. 505-510, july, 2020, doi: 10.18869/acadpub.ijrr.18.3.505.
[11] C. F. Yeap et al., ”Development of a Fluence Generating Programme for Patient Specific Quality Assurance and Calibration of an Amorphous Silicon EPID,” Journal of Physics, 2020, doi:10.1088/1742-6596/1505/1/012004.
[12] G. Razinskas et al., ” Sensitivity and Specificity of Varian Halycon’s Portal Dosimetry for Plan-Specific Pre-Treatment QA,” Journal of Applied Clinical Medical Physics , April, 2023, doi: 10.1002/acm2.14001.
[13] I. Mrcela et al., ”Dosimetric Verification of Intensity Modulated Radiotherapy (IMRT) Treatment Plans for Prostate Cancer Patients,” Acta Clin Croat, vol. 61, 2022, doi: 10.20471/acc.2022.61.s3.3.
[14] K. B. Kim, S. H. Choi., ’’ Postal Dosimetry Audits for the Domestic Medical Linear Accelerator,’’ Progress in Medical Physics. Vol. 31, no 2, June, 2020.
[15] K. M. Sergieva, ”Dosimetry Audit in Modern Radiotherapy,” Queen Giovanna University Hospital, Sofia Medical University, Sofia, Bulgaria.
[16] L. Duan et al., ” Evaluation of Complexity and Deliverability of IMRT Treatment Plans for Breast Cancer,” Department of Radiation Oncology, 2023, doi: 10.1038/s41598-023-48331-x.
[17] M. C. Glenn et al., ”Photon beam modeling variations predict errors in IMRT dosimetry audits,” J. Radiotherapy and Oncology, vol. 8, no. 14, 2022, doi:10.1016/j.radonc.2021.10.021.
[18] M. E. Kafhali et al., ” Clinical Experiment on Quality Control Comparison of Complex Treatment Plans of the VMAT Technique Using a Diode-Based Cylindrical Phantom (ArcCHECK) and an Amorphous Silicon-Based Planar Detctor (A-Si1000).” Elsevier B.V, vol. 12, November, 2021, doi: 10.1016/j.phmed.2021.100044.
[19] N. Dogan et al., ” Use of Electronic Portal Imaging Devices for Pre-Treatment andin vivo Dosimetry Patient-Specific IMRT and VMAT QA: Report of AAPM Task Group 307,” Med Phys, vol. 50, July, 2023, doi:10.1002/mp.16536.
[20] N. R. Kakade et al., ”Dosimetry audit in advanced radiotherapy using in-house developed anthropomorphic head & neck phantom,” Biomed. Phys. Eng. Express, vol. 10, Feb, 2024, doi:10.1088/2057-1976/ad222a.
[21] P. N. Mobit et al., ”End-to-End Test for a Radiotherapy Program Based on the Medical Linear Accelerator Installed in a Resource-Limited Oncology Centre in Sub-Saharan Africa,” Radiation Science and Technology, vol. 8, no. 2, pp. 22-29, doi: 10.11648/j.rst.20220802.1.
[22] F. C. D Zamo et al., ” Patient specific quality assurance of volumetric modulated arc therapy of synchronous bilateral breast cancer,” American Association of Medical Dosimetrists, vol. 49, November, 2023, doi: 10.1016/j.meddos.2023.11.003.
Published
2024-12-23
How to Cite
SALIMA, Syalima; SHABIRA, Nazwa Adhelia; PUTRI, Erlinda Ratnasari.
Audit Dosimetri pada Teknik IMRT/VMAT Terapi Radiasi pada Linear Accelarator (LINAC).
Progressive Physics Journal, [S.l.], v. 5, n. 2, p. 469-477, dec. 2024.
ISSN 2722-7707.
Available at: <https://jurnal.fmipa.unmul.ac.id/index.php/ppj/article/view/1443>. Date accessed: 15 jan. 2025.
doi: https://doi.org/10.30872/ppj.v5i2.1443.
Section
Articles
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
