Efek Pemanis Buatan Sakarin Dan Sari Buah Naga Merah (Hylocereus costaricensiss) Terhadap Histopatologi Hati Dan Ginjal Mencit (Mus musculus L.)

  • Ela Santi Mulya Sari Program Studi Biologi, Fakultas MIPA, Universitas Mulawarman
  • Sudiastuti Sudiastuti Program Studi Biologi, Fakultas MIPA, Universitas Mulawarman
  • Sudrajat Sudrajat Program Studi Biologi, Fakultas MIPA, Universitas Mulawarman

Abstract

This study aims to determine the effects of saccharin and dragon fruit juice on histopatologic of  liver and kidney and determine the effective dose of dragon fruit juice to improve the cells of liver and kidney mice (Mus musculus L.) after fed saccharin. The study design used was completely randomized design (CRD). In this study, the independent variables consist of two control and three treated treatment with 5 replications. The histological data of liver and kidneys of mice (Mus musculus L.) presented descriptively,and evaluation of differences in the structure of the liver and kidney mikroanatomi saccharin and dragon fruit (Hylocereus polyrhizus) be compared to normal structure. The results showed that administration of saccharin at a dose of 15mg/kg BB/day to given effect on the histopathology of kidney and liver of mice. Treatment of the red dragon fruit juice at a dose of 200mg/Kg BB/day may improve liver and kidney mikroanatomi structures damaged by the provision of saccharin. From this research, showed that the  red dragon fruit juice swetened with saccharin can inhibition effects of  on structure microanatomy the liver and kidney

Published
2017-06-04
How to Cite
SARI, Ela Santi Mulya; SUDIASTUTI, Sudiastuti; SUDRAJAT, Sudrajat. Efek Pemanis Buatan Sakarin Dan Sari Buah Naga Merah (Hylocereus costaricensiss) Terhadap Histopatologi Hati Dan Ginjal Mencit (Mus musculus L.). BIOPROSPEK: Jurnal Ilmiah Biologi, [S.l.], v. 11, n. 1, p. 65-68, june 2017. ISSN 2615-5435. Available at: <https://jurnal.fmipa.unmul.ac.id/index.php/bioprospek/article/view/129>. Date accessed: 27 apr. 2024. doi: https://doi.org/10.30872/bp.v11i1.129.

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